Sex hormone-like effects
Estrogen effect
The crab eel extract can extend the estrous period of normal female mice, and oestrus mice can show estrus, and make the uterus and ovaries (the normal mouse weight increase). The crab eel extract (GEA) has a direct effect on the accessory rat's uterus (uterus and vagina), but its complete function requires the ovarian, pituitary, and hypothalamus. The alcohol extracts from the crab body and tail can increase the weight of the uterus and ovaries of the young female mice, and the weight gain of the crab tail crab is stronger than that of the crab body. The body and tail were compared with the equivalence element respectively. The weight gain of the tail was higher than that of the equivalence element. The weight gain of the body was close to the equivalence element. The alcohol extracts from the crab body and tail can advance the vaginal opening time of young female mice, and the crab crab tail group is earlier than the crab body group.
Androgen-like effects
Taking the weight of the prostate, seminal vesicles, and levator ani muscles of the mice as indicators, the extracts of the crabs exhibited androgen-like effects. The ethanol extracts from the body and tail of crabs could increase the weight of seminal vesicles and prostate in castrated male rats. The weight gain of tails was stronger than that of testosterone. The alcohol extracts from crabs could shorten the incubation period of male fruit flies. By lengthening the mating time, the water-soluble portion of the crab extract can only make the testes of the male mice weight-enhanced and show an androgenic hormone-like action, while the fat-soluble part can increase the weight of the female mice's uterus and the male mice's testes. The sex hormone-like action of the crab tail crab is stronger than that of the crab body and may be related to the higher zinc content of the tail.
The crab extract of the crab has obvious antiasthmatic effects on guinea pig asthma caused by acetylcholine, and has direct relaxation effect on the isolated trachea of ​​guinea pigs, while the decoction of crab and crab has no obvious effect. However, it has also been reported that ethanol extracts have no relaxation effect on isolated tracheal smooth muscle of guinea pigs with histamine or acetylcholine-induced pain.
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